RANDOX Meprobamate ELISA

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Introduction:

Meprobamate is a drug marketed as a sedative, anxiolytic agent or muscle relaxant that has major potential for abuse and dependency, especially when combined with alcohol or other central nervous system depressants. In cases of overdose, meprobamate produces CNS depression and neurological symptoms including lethargy, stupor, slurred speech, headache, weakness and prolonged coma in extreme overdoses. In the United States, meprobamate is listed as a Schedule IV drug in the Controlled Substances Act. However meprobamate's parent drug carisoprodol, which is widely prescribed for musculoskeletal conditions, is not subject to federal control even though it has potential for abuse.

Cross Reactivity

Analyte Compound
Cross Reactivity %
Meprobamate
LOD: 7.64 ng/mL
Meprobamate 100
Carisoprodol
66.7
Meprobamate-N-β-D-glucuronide
15.2
 
Mebutamate
11