RANDOX Zopiclone ELISA

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Introduction:

The Z-drugs are a group of drugs commonly referred to as the "non-benzodiazepines" that may be prescribed for short term use to deal with severe sleeping difficulties. Z-drugs differ pharmacokinetically in their elimination half-lives, but are all short acting compared with classical benzodiazepines. Often users are unaware of the serious health risks involved in the misuse of these drugs including risk of coma, respiratory depression and death associated with excess doses in combination with alcohol or other CNS depressants. Reported psychosocial effects include depressed mental activity, memory loss, personality and mood changes, lethargy, disinhibition, chronic paranoia and aggression.

Cross Reactivity

Analyte Compound
Cross Reactivity %
Zopiclone
LOD: 2.99 ng/mL
Zopiclone 100
N-desmethylzopiclone HCI
109
Zopiclone-N-oxide
87
 
Eszopiclone
5