RANDOX Opiates ELISA

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Introduction:

Opium is obtained from the unripe seed pods of the opium poppy. Opium resin contains two groups of alkaloids: phenanthrenes (including morphine and codeine) and benzylisoquinolines (including papaverine). Morphine is by far the most prevalent and important alkaloid in opium, consisting of 10-16% of the total. Morphine remains a popular drug for the treatment of severe pain. Opiates work by decreasing the brains perception of pain and in addition can create feelings of euphoria.  This mood enhancement often leads to addiction and physiological dependence.  Side effects of opiates can include sedation, dizziness, nausea, vomiting, constipation, respiratory depression, physical dependence and tolerance.

 

Cross Reactivity

Analyte Compound
Cross Reactivity %
Opiate
LOD: 1.15 ng/mL
Morphine 100
6-Acetylmorphine
636.1
6-Acetyl-codeine
441.7
 
Thebaine
150.6
 
Codeine
104.3
 
Ethylmorhphine HCI
99.7
 
Desmorphine
82.4
 
Morphine 3βD Glucuronide
45.6
 
Morphine 6βD Glucuronide
34.5
 
Hydrocodone
22.1
 
Hydromorphone
20
 
Dihydrocodeine
15.3
 
Norcodeine
0.8
 
Normorphine
0.6
 
Noroxycodone
<1
 
Oxymorphone
<1
 
Oxycodone
<1
 
Noroxymorphone
<1