RANDOX Oxycodone ELISA

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Introduction:

Oxycodone is a semi-synthetic narcotic analgesic derived from Thebaine. The drug was synthesized in 1916 to improve on existing opioids in the hope that it would retain the analgesic effects of morphine and heroin with less dependence. To some extent this was achieved, as Oxycodone does not have the same immediate effect as heroin or morphine with a shorter action time.

Oxycodone is clinically used under the trade name OxyContin since 1939 for the relief of moderate to severe pain. At present, Oxycodone is the most widely abused opioid drug in America with around 100,000 emergencies admitted to US hospitals per year. In light of this, Oxycodone abuse has notably risen in recent years.

 

Cross Reactivity

Analyte Compound
Cross Reactivity %
Oxycodone
LOD: 3.85
Oxycodone 100
Hydrocodone
94.6
Noroxycodone
88.6
 
Codeine
1.3
 
Amitriptyline
<1
 
(R-) AMP
<1
 
Buprenorphine
<1
 
BZG
<1
 
Delta-8 THC
<1
 
Delta-9 THC
<1
 
Dextromethorphan
<1
 
Doxepin
<1
 
Fentanyl
<1
 
Imipramine
<1
 
Levorphanol
<1
 
Lorazepam
<1
 
Meprobamate
<1
 
Methodone
<1
 
Morphine
<1
 
Morphine-3-β-D-Glucuronide
<1
 
Morphine-6-β-D-Glucuronide
<1
 
Norcodeine
<1
 
Noroxymorphone
<1
 
Nortriptyline
<1
 
Oxazepam
<1
 
Oxymorphone
<1
 
PCP
<1
 
Phenobarbital
<1
 
THC COOH
<1
 
Thebaine
<1
 
Tramadol
<1
 
Zolpidem
<1