CM Cellthru BigBead Plus [EQUL-BSM29] Equl offers Enzyme Assay Kits, Reagent Mixtures, Enzymes, Glycobiology, Amylase Test, Carbohydrase Tablet Tests, Protease Tablet Tests, Cofactors and Stains, Soluble Chromogenic Substrates, Insoluble Chromogenic Substrates, etc 

CM Cellthru BigBead Plus

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EQUL-BSM29 CM Cellthru BigBead Plus EA call for price none
Product Code11022
Bead Size300-500µm
Matrix Structure4% agarose, hardened
Flow rate5000cm/h*
Binding Capacity50mg BSA/ml resin
Cleaning0.5M NaOH
Storage Conditions20% ethanol, 2-8C
Temperature stability range0°- 60°C
Functional ligandCarboxyl
Ion Exchanger TypeWeak cation
Counter ionNa+
pH stability range2-14
Chemical stabilityCommon aqueous, organic, high salt, denaturants
Physical stabilityNegligible volumbe changes due to pH or Ionic state
Drug master fileU.S. Food & Drug Administration

*Flow rate determined in a 1.5x5cm column

- Large particle diameter allows crude material to pass through the column with little to no backpressure during direct capture
- Four different ion exchange chemistries can be used with a variety of bead sizes
- Highly robust, chemically stable beads are ideal for process-scale separations
- High product recovery, up to 95%
-cGMP manufacturing; Regulatory Support File available

Ion exchange Cellthru BigBead Plus resins are made of a hardened agarose matrix with ion exchange groups attached through a spacer arm. Hardening increases the chemical and mechanical stability of the matrix. CM Cellthru BigBead Plus is a large particle, weak cation exchanger where capacity is a function of pH.

Cellthru BigBeads can be used for viscous feed streams and direct capture and also function in standard packed-bed applications using specially manufactured columns. Scale up from pilot to production scale follows a linear relationship, reducing the time spent on method development.